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Additionally, the increased levels of citrate in the cytoplasm activate the key regulatory enzyme of fatty acid biosynthesis, acetyl-CoA carboxylase (ACC) while at the same time citrate allosterically inhibits the rate-limiting enzyme of glycolysis, PFK-1

To achieve this, the researchers partnered with Creative Proteomics for targeted quantification of erythrocyte glutathione and its oxidized form (GSSG)
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Glutathione is an important antioxidant that is primarily made by the body

Chapter Three - A Pipeline for Studying and Engineering Single-Subunit Oligosaccharyltransferases
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