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This raises the question of whether the efficacy of anti-EGFR therapies in CRC patients depends on EGFR inhibition in tumor cells, myeloid cells, or both

Normal biogenesis of mitochondria is triggered in response to changes in the ATP/ADP ratio and to activation of AMPK which in turn results in increased expression of PPAR co-activator 1 (PGC-1) and nuclear respiratory factor-1 (NRF1)

NAPstars exhibit several other advantages over currently available NADP sensors including a limted pH sensitivity (Supplementary Fig

Li X, Xu P

Up to 200 ng of each cDNA sample, based on the PicoGreen quantification, was sheared (mechanically fragmented) using the E220 Focused-ultrasonicator Covaris (Covaris)