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The dominant preclinical models are: rodent water-maze and active-avoidance for learning and memory
Accumulation of senescent cells in tissues has been associated with age-related functional decline, chronic inflammation, and impaired tissue regeneration
Toxicol Rep 8:646656
Dosing Discrepancy: The effective in vivo doses (1 g/mouse) are micro-doses compared to the mega-doses (10 mg/day) used in human biohacking and clinical trials
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