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The zebrafish is evolving from a basic model into an intelligent, translational drug discovery engine, accelerating plant-derived anti-inflammatory applications and enabling precision treatment of inflammatory diseases

It can be given via IV or injection

Each of the compounds transported by the SMVT is competitive with the others
A wheal-and-flare reaction is a result of immunoglobulin E-dependent basophils and mast cells activation

These findings suggest isoform-selective HDAC inhibitors could provide more precise and safer therapeutic strategies compared with broad-spectrum HDAC blockade
