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Nicotine is the main harmful substance in cigarettes, and nicotine affects male reproductive function by disrupting blood-testis barrier dynamics [108]

References Myers, R

Bao W, Zhou X, Zhou L et al (2020) Targeting miR-124/Ferroportin signaling ameliorated neuronal cell death through inhibiting apoptosis and ferroptosis in aged intracerebral hemorrhage murine model

(2010) Location, location, location: Compartmentalization of early events in leukotriene biosynthesis

It has been reported that 20% of the active ingredients in plants, including terpenoids, flavonoids, and steroids, have significant potential as drugs (Yu et al., 2022)