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65 At 37 M, ANS accelerates degradation of phosphorylated connexin 43 (Cx43) by activation of p38
International Journal of Molecular Sciences , 18 (1), 197

Cairns et al., 2006)

Moreover, multiple in vitro (64,65) and in vivo (66,67) studies suggest that ergothioneine activates the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), which triggers the cellular antioxidant defence system

Skin and liver tissues were rinsed in cold PBS, weighed (0.1 g), homogenized in 1 mL of extraction buffer, and sonicated on ice
