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How Proxofim (FOXO4-DRI) Works The D-retro-inverso modification reverses the peptide sequence and replaces L-amino acids with D-amino acids

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A Little Experiment Can Go a Long Way The lesson in all this is being willing to experiment

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Maqueda, A

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IRS-2, insulin receptor substrate 2

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The orbitrap parameters were a noise threshold of 5 10 3 for MS1 and 2.5 10 3 for MS2, a minimum feature height of 5 10 4 , and m/z tolerances of 10 ppm (scan-to-scan), 5 ppm (intra-sample), and 5 ppm (inter-sample)

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