glutathione peroxidase 1 uniprot Suitable for ICC/IF RCSB PDB - 1GP1: THE

This can be particularly beneficial for individuals suffering from inflammatory conditions such as arthritis or chronic muscle strains

Another natural polyphenol with neuroprotective properties is resveratrol (RES) due to its antioxidant property and ability to protect mitochondria

Only the selenium-dependent enzyme glutathione peroxidase can convert hydroperoxides into non-toxic compounds, through the reaction: As a conclusion of the role of selenium in the antioxidant defense system, it can be said that even if vitamin E is the most known antioxidant, selenium is indispensable for the complete transformation of free radicals into non-toxic compounds

Sjovall 1959)

Tyr515 phosphorylation allows for the docking of Shc to the receptor to initiate the PI3K/Akt pathway [51], which regulates the activity of various proteins necessary for neuron existence, such as BAD (Bcl-2 antagonist of cell death) and GSK-3 (Glycogen Synthase Kinase 3) [52]