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They regulate synaptic transmission by taking up and metabolizing neurotransmitters such as GABA and glutamate [193], releasing gliotransmitters [21] and protecting RGCs from glutamate-induced excitotoxicity [194]

Metabolism In adults, the primary metabolic pathway for paracetamol is glucuronidation

doi: 10.21608/avmj.2013.191997 160

Nicotinamide Preservation 5-Amino-1MQ functions as a NAM-site competitive inhibitor, binding at the active site of NNMT and preventing the enzyme from methylating nicotinamide

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