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Mice from each group (n = 5) were killed at the conclusion of the experiment and immunohistochemical analysis was performed

Only GlyNAC supplementation in OA resulted in significantly improved (a) GSH concentrations by 121% after 2-weeks, and by 164% after 16-weeks to levels not different from YA-0w (Supplementary Figure S1), and (b) muscle GCLC and GSS expression (with a trend toward improvement for GCLM

& McAlary, L

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