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glutathione therapy from prodrugs to genes Dendrimers as Non-Viral Vectors in Gene-Directed Enzyme Prodrug Gene Directed Enzyme Prodrug Therapy
Description
[26] In cell cultures where N-acetylcysteine (NAC) (an efficient thiol source and glutathione precursor) is added, the activation of NF-kB is blocked (Figure 1)

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Choline is essential for phosphatidylcholine synthesis, neurotransmitter production (acetylcholine), and hepatic VLDL export

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However, succinyl-CoA can also be generated through the catabolism of other amino acids, such as isoleucine, or the short-chain fatty acid propionate, produced by gut bacteria
