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This encouraged the research for a possible action of the peptide in humans suffering from chronic pronounced pain episodes

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Formulation flexibility: Lipotropic injections can be customized by compounding pharmacies to meet specific patient needs, enabling more personalized care

Dexamethasone combined with berberine has also shown antifibrotic effects, which involve inhibiting C-X-C motif chemokine ligand (CXCL)-14 and MMP-2/MMP-9 expression and preventing the activation of Smad2/3 and hedgehog signaling pathways [123]

However, its bioavailability is relatively low and it is easily metabolized and degraded in vivo