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Microbiota-modulating interventions reinforce this connection

Mechanistic studies link disrupted one-carbon metabolism, elevated homocysteine, and mitochondrial dysfunction in B12 deficiency to pathways implicated in Alzheimers disease, supporting investigation of B12 in neurodegeneration [3]

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Curr Top Microbiol Immunol 295:275291 Becker K, Tilley L, Vennerstrom JL, Roberts D, Rogerson S, Ginsburg H (2004) Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions

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