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NNMT is a cytosolic enzyme that methylates nicotinamide (vitamin B3) using S-adenosylmethionine (SAM) as a methyl donor
Factors like aging, alcohol consumption, and environmental toxins can impact how efficiently B12 is processed, leaving you feeling depleted
It's working heroically to keep everything running despite the oxygen deficit
This mechanical unloading allows damaged cartilage to recover to some degree and reduces inflammation
