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Dissimilar patterns of promotion by di(2-ethylhexyl)phthalate and phenobarbital of hepatocellular neoplasia initiated by diethylnitrosamine in B6C3F1 mice

3.5 Meta-analysis The included studies showed substantial heterogeneity (I 2 = 99.6%, p 0.05), supporting the conclusion of comparable efficacy and the lack of a clear doseresponse relationship

Moreover, supplementation with EPA and DHA has been shown to modulate nociceptive responses, potentially through activating the opioid system, offering benefits in neuropathic pain scenarios

doi:10.1042/BJ20041217

Many systemic inflammatory conditions have gastrointestinal components that benefit from this approach