glutathione peroxidase thyroid gland (GPx) redox cycle. The main reaction that Selenium | Linus Pauling Institute
Description
What do they actually do
Luteolin Lignans, derived from traditional Chinese herbs, have been recognized for their potential cardioprotective effects mediated through multiple signaling pathways

Hironaka S, Sugimoto N, Yamaguchi K et al (2016) S-1 plus leucovorin versus S-1 plus leucovorin and oxaliplatin versus S-1 plus cisplatin in patients with advanced gastric cancer: a randomised, multicentre, open-label, phase 2 trial
The problem arises if the free radicals oxidize LDL, proteins, or DNA as shown below

The mechanism of action begins when Kisspeptin-10 binds to the KISS1R receptor on GnRH neurons in the hypothalamus
