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One proposed mechanism involves impaired clearance of proteinbound uremic solutes, which are normally excreted by the kidneys

[PubMed: 12458094] 218

It even appears that it could find future application in the research of depression or cancer

Doses of 0.6 mL/d, administered three times a day for one month, and 1 mL/d, divided into three doses over two months, were assessed for their impact on haemoglobin, blood counts, liver and kidney functions, bleeding and clotting time and serum electrolytes