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The mechanism by which TMAO promotes the complex pathological processes of atherosclerosis is gradually being elucidated and includes cholesterol accumulation, activation of pro-inflammatory pathways, endothelial dysfunction, and thrombosis (62) ( Figure 3 )
6-Bromo-6-deoxy-l-ascorbic acid: An ascorbate analog specific for Na+-dependent vitamin C transporter but not glucose transporter pathways
