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Methodologies for bioactivity assay: Biochemical study
Malaisrie SC, Hofstetter WL, Correa AM, Ajani JA, Komaki RR, Liao Z, Phan A, Rice DC , Vaporciyan AA, Walsh GL, Lahoti S, Lee JH, Bresalier R, Roth JA, Swisher SG
The published preclinical literature uses weight-adjusted rodent dosing that doesn't translate cleanly to fixed human protocols, so researchers extrapolate
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