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Lineage tracing of peri-injury AXIN2 hepatocytes has shown that, during recovery, AXIN2+ liver cells regenerate and repair damaged substances

Cisplatin exacerbates hair cell damage through a dual mechanism: on the one hand, it activates nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy, which prompts ferritin to release free Fe 2+ , generating a large amount of reactive oxygen species (ROS) via the Fenton reaction and inducing a lipid peroxidation chain reaction (Dai et al., 2024)

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.He B., Wang F., Qu L

A limited number of studies have reported increased systemic levels of claudins as a marker for impaired intestinal barrier function, e.g., increased serum claudin-5 in children with attention deficit hyperactivity disorder (67) and increased urinary claudin-3 in patients with active Crohn's disease which was associated with decreased claudin-3 staining in intestinal biopsies (68)

What are serums and why they are getting so popularity nowadays