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The large heterogeneity for some outcomes, such as CAD, may suggest different mechanisms underlying the genetic associations or the existence of pleiotropy [37]

10.1124/mol.59.2.358 Mol
DEXA administration was shown to stimulate the development of IR [10,11,12,13] and NAFLD in numerous reports [9, 14, 41]

Related to epigenetic considerations, the level of mtDNA mutations positively correlates with BACE1 activity in aging, DS, and DSAD specimens, whereas mtDNA copy number is inversely correlated with insoluble A40 and A42 levels (437)

M.KayeR.HoangV.RongS
