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[DOI] [PMC free article] [PubMed] [Google Scholar] 97.Wu A., Lee D., Xiong W.C., Metabolism L

Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis

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To explore whether there are other endogenous-exogenous synergistic systems capable of efficiently suppressing ferroptosis, we screened the FDA drug library and natural product library in ferroptosis induced by the GPX4 inhibitor RSL3, to identify new suppressors through utilizing high-throughput screening based on high-content screening and image analysis (Fig