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PSA is also widely used to monitor responses to therapy and is under investigation as a therapeutic target

Concurrently, elucidating the interaction mechanisms between the brain and peripheral organs such as the gut and spleen may not only reveal novel pathways for pathological propagation but also uncover a series of entirely new intervention targets

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The convergence of these mechanisms establishes a strong biological rationale for targeting metabolic intermediates AKG, thereby supporting further investigation of AKG-related pathways in preclinical and translational studies of NDDs

10.3390/ijms21239044 225 ParlatiL.VoicanC