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This enables CP17 to adopt a different conformation
CKD can affect the metabolism of some nutrients, and supplementation may not be advisable in those with advanced CKD
When assessing for vitamin B12 deficiency, in addition to checking a vitamin B12 level, consider ordering a methylmalonic acid level or a holotranscobalamin level and CBC (to assess for red blood cell size)
doi:10.1111/j.1365-2036.2012.05051.x