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A proportional shift from glucose dependence to FAAO utilization and simultaneous upregulation of several metabolic pathways underly immune-suppressive phenotypes tol-DC We next applied single-cell approaches to investigate DC skewed to be tolerogenic to identify critical metabolic features and potential biomarkers defining the major modes of in vitro tolerogenic DC generation

Briefly, the aqueous solution of liposome or BSA or pBR322 was -irradiated (50300 Gy) in the presence and absence of DSePA, and the level of lipid peroxidation or protein carbonylation or strand-breaks was measured through standard biochemical assays [86]

For example, much of NACs antioxidant potential has been associated with a purported ability to increase glutathione (GSH) production, GSH being a powerful antioxidant in its own right

doi: 10.2147/IJN.S196472, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Chowdhuri A