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Furthermore, CD8 + T cells use IDO1 by the Kyn pathway to produce nicotinamide adenine dinucleotide (NAD), which is essential for metabolism and antitumor activity [117]

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Common side effects may include: Blue urine Stained mouth or teeth Headache or dizziness Altered sense of taste Pain in your extremities Sweating Nausea Notify your caregiver or doctor right away if you experience: Allergic reaction (e.g., swelling of face, difficulty breathing, or hives) Sudden fever Pale or yellow skin Weakness Confusion Shortness of breath Chest pain Blue hands or feet Other side effects may also occur

( PcGST1 possibly affected the CHS transcription by changing the redox state