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There is limited evidence that IV infusions provide general health, "wellness", energy or anti-ageing benefits in people who do not have a diagnosed deficiency or medical need, and we cannot guarantee any specific outcome

Individuals with cardiovascular conditions or stimulant sensitivity should seek medical guidance before using high-caffeine products

doi: 10.1016/j.bcp.2009.03.003

doi: 10.1016/j.arr.2012.06.006

Since night shift work is associated with the hypermethylation of genes involved in the circadian biorhythm [180], which is also involved in changes in melatonin secretion [112], it is plausible that melatonin may also directly change DNA methylation