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Since Fe 2+ in the labile iron pool is the specific substrate for ferroptosis, and rises with aging in C

W., An, R., & Clinton, S
Cell studies in lung cancer show that NAC has the ability to detoxify chemicals as a precursor of reduced glutathione, scavenging of radicals, and protection from DNA damage

This results in a deficiency of MTHF, which in turn leads to a deficiency of SAM
