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For example, knocking out PDGF-R resulted in loss of bloodbrain barrier function in pericyte-depleted mice, demonstrating the importance of pericytes in maintaining the functional integrity of the BBB[26]

doi: 10.3390/ijms21020667

Stephanann Costello provided feedback on the written manuscript

In this cycle pyroglutamate, also known as 5-oxoproline, is degraded by the ATP dependent enzyme 5-oxoprolinase into glutamate
