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Furthermore, CPI-613 suppresses the proliferation of multiple myeloma cells by inducing mitochondrial metabolic dysfunction through the targeting of pyruvate dehydrogenase E1 subunit alpha 1 (PDHA1) and oxoglutarate dehydrogenase (OGDH), and it produces significant anti-tumor effects when combined with bortezomib at a lower dose [88]

Based on this criterion, a mutant library of S

Radiotherapy for mesothelioma

Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

Nevertheless, other randomized clinical trials failed to demonstrate any beneficial effect of selenium supplementation in GD (81, 82) or in HT [79, 80]