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Description
Carotenoids have strong antioxidant properties, and help facilitate communication between cells by promoting the synthesis of connexin proteins, which create gap junctions in cell membranes that allow small molecules to be exchanged (which is part of how cells talk to each other!)

TriMix commonly includes three medications: alprostadil, phentolamine, and papaverine, hence the tri in the name

doi: 10.1038/s41564-018-0334-0 136 LaichalkLLThorley-LawsonDA

Mild myasthenia has occurred in uremic patients receiving D,L-carnitine (but not levocarnitine)

The clinical study Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) conducted in and mild to moderate TG elevation at baseline (200499 mg/dL) and HDL-C 40 mg/dL patients with diabetes randomized to placebo or pemafibrate included patients achieving LDL-C target after statin therapy who did not show a difference in clinical events between the two groups, which raises the question of whether TG reduction by fibrates reduces ASCVD risk ( TABLE 10 Management of high TG
