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Effect of leptin deficiency on metabolic rate in ob/ob mice

10.1016/j.freeradbiomed.2020.07.037 58 NelsonK

This mechanism contributes to synergistic benefits when both hormones are optimized but also explains why growth hormone therapy can unmask borderline thyroid insufficiency that was previously compensated

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Cycling and Breaks Some peptides benefit from cycling (periods on and off) to maintain effectiveness and prevent desensitization
