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Advanced Glycation End-products suppress mitochondrial function and proliferative capacity of Achilles Tendon-Derived fibroblasts

And it powers sirtuins, proteins that repair DNA and generally keep the cell tidy

Delayed gastric emptying extends the time B12 spends in the acidic stomach environment, which might initially seem beneficial

Worked example: 10 mg vial with 2 mL water Concentration: 10 mg divided by 2 mL = 5 mg/mL For a 2.5 mg dose: 2.5 divided by 5 = 0.50 mL = 50 units For a 5 mg dose: 5 divided by 5 = 1.0 mL = 100 units For a 7.5 mg dose: 7.5 divided by 5 = 1.5 mL = 150 units (requires a larger syringe or two draws) Worked example: 30 mg vial with 3 mL water Concentration: 30 mg divided by 3 mL = 10 mg/mL For a 2.5 mg dose: 2.5 divided by 10 = 0.25 mL = 25 units For a 5 mg dose: 5 divided by 10 = 0.50 mL = 50 units For a 10 mg dose: 10 divided by 10 = 1.0 mL = 100 units For a 15 mg dose: 15 divided by 10 = 1.5 mL = 150 units Notice how the 10 mg/mL concentration makes the math cleanest