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There is also a need to better understand the relationship between alcohol intake and reproductive outcomes (particularly anovulatory infertility) [139], as safe alcohol limits in PCOS is currently unknown [139]

Many of these trials recruited terminal or end-stage patients, for whom any sort of treatment is unlikely to have an effect, and they often recruited cohorts with mixed cancers, which may respond differentially to IVC depending on the underlying mechanisms involved

Consistent with the role of LILRB1 in cholesterol uptake [47], subsequent analysis of LILRB1 KD MM cells from the mice confirmed they contained lower levels of intracellular LDL-cholesterol than MM cells from the control mice [47]

Finally, a total of 5,575 participants were included in the present study

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