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[DOI] [PubMed] [Google Scholar] 114.Vetter ML, Faulconbridge LF, Webb VL, Wadden TA

Approaches include redox interactions with high-valent metal ions (like Cu 2 and Fe 3 ), suppression of GSH synthesis using agents such as BSO, the use of nanozymes that mimic enzymatic activity, and direct GSH neutralization through molecular binding [18]

124 Induced pluripotent stem cells were prepared from BSEP-deficient patients ( ABCB11 mutation) and differentiated into hepatocyte-like cells

(NCT01371357, NCT00102843, NCT00126347, NCT01950039, NCT04633044, and NCT06042270)

As highlighted elsewhere [184], neurons rely heavily on astrocytes for redox balance, creating a compartmentalized and interdependent defense system