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& Dryhurst, G

Reduziertes Glutathion (GSH) als Antioxidans: Reduziertes Glutathion (GSH) spielt eine wichtige Rolle bei der Reduzierung von oxidativem Stress durch freie Radikale

Timing of intervention is critical, with early application during reperfusion being most effective to prevent irreversible DNA damage and mitochondrial injury

The exact coupling of the steps is still partly unknown

Density functional theory (DFT) calculations of the reaction mechanism suggest that the isomerization involves base-catalyzed deprotonation of C-6 followed by protonation of C-4, while the oxidation occurs via a free radical mechanism [567]