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Cerebellar hypoplasia in mice lacking selenoprotein biosynthesis in neurons

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In the Phase 2 study the highest arm continued upward toward higher maintenance targets, but the core principle held throughout: escalate only after the current step is tolerated , in roughly four-week increments

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The first hypothesized mechanism is via the stimulation and secretion of the VEGF, leading to the growth of blood vessels in the area surrounding the hair follicles

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