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It can depend on what happened earlier that day
This ligand-directed approach reduces systemic toxicity, enhances drug bioavailability at the site of interest, and improves therapeutic outcomes, particularly in tumours with heterogeneous receptor expression profiles [117]
For instance, a rapid reduction of the disulfide can be caused by a second cysteine nearby, as happens in the active sites of glutaredoxin (Grx) or thioredoxin (Trx)
Apoptosis 8 , 481495 (2003)
FBP17N-WASPCdc42 cooperatively form curvature-dependent nucleation hotspots that couple global Cdc42 signals to local geometry
