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Development was accomplished with either diaminobenzidine-based Elite (for Iba1) or Vector Red (other immunostains) kits (Vector Laboratories, Burlingame, CA)

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Reconstituted AOD-9604 should be stored at 28C, protected from light, and used within 30 days

Symptoms of MCAS include flushing, itchy skin, low blood pressure, constipation and/or diarrhea, abdominal pain, shortness of breath, and nasal congestion.[ref] The symptoms of MCAS are driven by excess histamine and overlap with histamine intolerance

Comparing ferroptosis and cuproptosis, it is interesting to note that mitochondria play a critical role in these two different types of cell death