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Reasons why mitochondria might be impaired or damaged include: Aging Inadequate diet Poor sleep Lack of exercise Genetics Heavy and toxic metals Pollutants Free radicals Prescription drugs Alcohol There are many conditions that are caused or made worse by mitochondrial dysfunction, such as the following per Pizzorno (2014): Early aging Amyotrophic lateral sclerosis Alzheimers disease Autism Cardiovascular disease Chronic fatigue syndrome Dementia Diabetes Huntingtons disease Migraine headache Parkinsons disease A great way to directly influence the health of our mitochondria is through the use of peptides

The treatment also decreased pro-inflammatory and pro-fibrotic gene expression with reduced macrophage infiltration (Li et al., 2025)

This condition remains untreated, yet it significantly influences cognitive decline and stroke incidence among older individuals

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The enzyme also keeps mitochondria efficient and helps it perform under stress