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When NF-kB activity is elevated, cells may produce more inflammatory signals such as TNF-alpha, IL-6, IL-8, and related mediators
An even more prominent Lewy body-like histopathology was observed in viral vector-based models overexpressing human mutations of SYN (e.g., A53T) (187)
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Graphical Abstract Access this article Similar content being viewed by others Data availability All source data for this work (or generated in this study) are available upon reasonable request
Cell 171 , 683695 (2017)
