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Instead, the sponsor notifies the TGA about the trial and provides details of the investigational product

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GSH depletion was negatively correlated to motor function performance

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Methods Study design This study presents outcome data on cognition and wellbeing from a randomized, open-label, clinical trial conducted at one university hospital (VU University Medical Center, Amsterdam, The Netherlands) which compared de- and increasing GH dose for 24 weeks with low-normal and high-normal IGF-1 target levels for efficacy and safety measures of GH replacement therapy [37]

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Transitioning to smaller, lower-fat meals in particular benefits from at least one to two weeks of consistency before starting the medication

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