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Studies have shown that they can accumulate in mitochondria and cross the BBB in small amounts
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World J Gastroenterol 23:38503863

doi: 10.4103/0250-474X.117438 72

If you have a B12 deficiency, you may be able to get hydroxocobalamin injections prescribed on the NHS

Histological features analysis showed that nerve fibers were mainly enriched in the middle part of the dermis and the papillary layer region, while the epidermal basement membrane zone, skin vascular network, and accessory microenvironment (such as hair follicles, sebaceous glands, etc.) showed specific distribution characteristics of sensory nerves (87)
