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Between 65% and 96% of participants taking orforglipron achieved an A1C level below 7.0% at 26 weeks

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[8] Across the broader published BPC-157 literature spanning gastrointestinal, musculoskeletal, dermal, vascular, and CNS research mortality in BPC-157-treated groups has generally been reported as comparable to vehicle-treated controls, and no consistent pattern of clinical deterioration has been established as a peptide-specific toxicity signal

These findings support the hypothesis that dampening of the GH pathway is the key contributor to lifespan extension in mice
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