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Divalent metal transporter 1 (DMT-1) present in the endosome reduces ferric iron (Fe 3+ ) to Fe 2+ , which participates in the electrochemical Fenton reaction with hydrogen peroxide (H 2 O 2 ) and produces deadly ROS

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Melanoma skin cancer Doctors sometimes use the term lesion to describe a finding on the skin

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Mutations in the Ldlr gene are the most common cause of familial hypercholesterolemia (FH), an autosomal dominant disorder associated with elevated levels of LDL-C and increased risk for premature cardiovascular disease (218)

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