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from Yale School of Medicine

10.1097/TP.0b013e3182298a15 55 OsadaR.OhshimaH.IshiharaH.YudohK.SakaiK.MatsuiH.et al (1996)

It is the mechanism by which the therapy works at all

Maternal immunization and vitamin a sufficiency impact sow primary adaptive immunity and passive protection to nursing piglets against porcine epidemic diarrhea virus infection

Through MT2 receptor stimulation, melatonin causes a cascade of downstream activation of protein kinase C (PKC), phosphorylation, and inactivation of GSK-3 leading to the reduction of tau hyperphosphorylation (Shi et al., 2018)
