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Chitosan and radiation chemistry

doi: 10.1016/j.imlet.2020.09.006 40 ZhaoYZhouJLiuDDongFChengHWangWet al

Results are presented as mean SD (n = 6) (K el - elimination rate constant, t 1/2 -plasma half-life, Cl-drug clearance, AUC-area under curve, C max -maximum concentration of the drug, T max -the time taken by a substance to reach the C max , AUMC-A under the moment curve, MRT-mean residence time, and Ka-rate of absorption)

In particular, iTregs generated in the presence of TGFb and rapamycin led to a polyclonal product enriched in FOXP3 + CD25 + CD4 + T cells that was clinically evaluated, depicting a favourable profile encouraging the phase II component for efficacy assessment [38]