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Description
This matters for dosing because beta-3 receptor sensitivity varies throughout the day and in response to nutritional status

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Pre-existing inborn errors of sulfur-amino-acid metabolism (e.g., homocystinuria) represent an absolute contraindication because parenteral methionine can exacerbate elevated homocysteine concentrations and associated thrombotic risk

This can reduce sluggishness and enhance stamina, making consistent activity more manageable