glutathione conjugation acetomenephin 54 ACETAMINOPHEN-INDUCED HEPATOTOXICITY - Drug Metabolism
Description
So 5 is 100x more acidic than 7 (10x10=100), and 13 is one million times more basic than 7

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S-adenosyl-L-methionine, derived from methionine, serves as the substrate for SAM-dependent methyltransferases, which catalyze the transfer of its methyl group
The distinction matters once you start comparing options

Rational siRNA design for RNA interference
