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Similarly, after treatment with azelaic acid, the expression of KLK-5 and cathelicidin mRNA, factors associated with major rosacea pathophysiologic pathways as previously described, decreased in patients with rosacea as well [141]

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And it inhibits the release of neuropeptides from trigeminal and parasympathetic nerve endings reducing the inflammatory cascade that causes sneezing and itching

doi: 10.1371/journal.pone.0007052 10 AshP

Natures version of terrain modulation
